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Titolo/Abstract/Parole chiave

Modified U1snRNAs as innovative therapeutic strategy for inherited coagulation factor deficiencies

Balestra, Dario (2012) Modified U1snRNAs as innovative therapeutic strategy for inherited coagulation factor deficiencies. Tesi di Dottorato , Università degli studi di Ferrara.

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    Abstract

    The theoretical framework in which this study is framed concerns the internationalization of production dynamics of firms abroad. The international literature in this field argues that there is not a conventional definition nor a universally tested theory that can explain all forms of foreign-owned production (see, among others, Dunning, 1988b and 1993a, Ietto-Gillies, 2005 and 2007). In this complex context, a large amount of Italian literature has been published around the theoretical framework of internationalization of production of Italian companies abroad (Tattara, Corò and Volpe, 2006, Mariotti and Mutinelli, 2005, et.al.). Nevertheless, a limited number of quantitative studies are available about the topic of Italian firms “migration” in Romania - as a particular expression of productive internationalization of our companies in this Country (Majocchi, 2002, Unimpresa Romania, 2005 and Antenna Veneto Romania, 2005). Thus, in order to investigate it by an industrial policy perspective a multilevel modelling approach has been applied. In particular, a two level model has been used to determine the effects of Romanian regions (romanian judets) in which Italian manufacturing firms internationalized the production in 2009 on their industrial performance. Based on a business register-based survey a business register of the Italian business community in Romania has been created. The data on Italian manufacturing firms located in Romania in 2009 have been selected from this register. The dataset used for the analysis includes 796 cases of firms internationalized in Romania. Therefore, a two level model has been carried out in order to determine the effects of intra-industry characteristics of these firms (i.e. Firm size and Firm Industrial specialization) on their industrial performance in 2009 both at individual and area level. The model results have shown that: as the firms dimension increase they have to be extremely sensible in the choice of the romanian region in which they want to (de)localize the production. Furthermore, the choice of the romanian region of productive delocalization has to be chosen by firms according to their sectors of activity.

    Tipologia del documento:Tesi di Dottorato (Tesi di Dottorato)
    Data:24 Febbraio 2012
    Relatore:Bernardi, Francesco - Pinotti, Mirko
    Coordinatore ciclo:Bernardi, Francesco
    Istituzione:Università degli studi di Ferrara
    Dottorato:XXIV Anno 2009 > BIOCHIMICA, BIOLOGIA MOLECOLARE E BIOTECNOLOGIE
    Struttura:Dipartimento > Biochimica e biologia molecolare
    Soggetti:Area 05 - Scienze biologiche > BIO/11 Biologia molecolare
    Parole chiave:splicing, U1snRNA, coagulation, coagulazione, RNA processing, processamento RNA
    Depositato il:20 Feb 2013 15:25

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